SecProbe.io

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        Wyrick Robbins Yates &
        Ponton LLP

        ATTORNEYS AT LAW

        4101 Lake Boone Trail, Suite
        300, Raleigh, NC 27607

        PO Drawer 17803, Raleigh, NC
        27619

        P: 919.781.4000 F: 919.781.4865
        www.wyrick.com

December 12, 2018

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, DC 20549

 Attention: Ms. Dorrie Yale

Ms. Irene Paik

Division of Corporation Finance

Office of Healthcare & Insurance

 Re: Eyenovia, Inc.

Draft Registration Statement on Form S-1

Filed November 21, 2018

File No. 377-02385

Ladies and Gentlemen:

We write this letter on behalf of our client Eyenovia, Inc.
(the “Company”) in response to the comments of the staff (the “Staff”) of the U.S. Securities and Exchange
Commission with respect to the above-captioned filing, as set forth in the Staff’s letter dated December 4, 2018. For ease
of review, we have set forth below in italics each of the numbered comments of the Staff’s letter and have followed each
comment with the Company’s response thereto.

Draft Registration Statement on Form S-1

Cover Page

 1. Please revise your prospectus to disclose the number of shares of common stock being offered. For guidance, please refer
to Rule 430A and Compliance and Disclosure Interpretations, Securities Act Rules, Question 227.02.

We acknowledge the Staff’s comment and have updated the
prospectus to disclose the number of shares of common stock being offered.

    U.S. Securities and Exchange Commission

December 12, 2018

Page 2

Description of Securities, page 19

 2. We note that your certificate of incorporation provides that the Court of Chancery of the State of Delaware will be the
sole and exclusive forum for any derivative action or proceeding brought on your behalf.  Please revise this section to include
disclosure regarding this provision.  Your disclosure should include a discussion regarding whether your exclusive forum
provision applies to actions arising under the federal securities laws.  In this regard, we note that Section 27
of the Exchange Act creates exclusive federal jurisdiction over all suits brought to enforce any duty or liability created
by the Exchange Act or the rules and regulations thereunder.

We acknowledge the Staff’s comment and have updated the
disclosure on page 19 of the prospectus. The exclusive forum provisions contained in our certificate of incorporation only apply
to “to the fullest extent permitted by law,” as provided in Article X. Accordingly, the provisions do not designate
the Court of Chancery as the exclusive forum for any derivative action or other claim for which the applicable statute creates
exclusive jurisdiction in another forum, such as the Exchange Act and the Securities Act. We have updated the disclosure on page
19 of the prospectus to expressly reference this fact.

* * * * *

The Company respectfully submits that the foregoing is appropriately
responsive to the Staff’s comments. If the Staff has any further comments, please direct
them to the undersigned.

    Sincerely,

    /s/ S. Halle Vakani

    S. Halle Vakani

 cc: Tsontcho Ianchulev, Chief Executive Officer, Eyenovia,
Inc.