CORRESP Filing
Ensysce Biosciences, Inc.
Date: Dec. 9, 2025 · CIK: 0001716947 · Accession: 0001493152-25-026751
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File numbers found in text: 333-291892
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CORRESP
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filename1.htm
Ensysce
Biosciences, Inc.
7946
Ivanhoe Avenue, Suite 201
La
Jolla, California 92037
December
9, 2025
VIA
EDGAR
U.S.
Securities and Exchange Commission
Division
of Corporation Finance
Office
of Life Sciences
100
F Street, NE
Washington,
D.C. 20549
Attention:
Timothy L. Buchmiller, Esq.
Re:
Ensysce
Biosciences, Inc.
Registration
Statement on Form S-3
SEC
File No. 333-291892
Filed
December 2, 2025
Ladies
and Gentlemen:
Pursuant
to Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, Ensysce Biosciences, Inc.
hereby requests that the effective date of the above-referenced Registration Statement be accelerated to 4:00 PM, Eastern Time, on December
11, 2025, or as soon thereafter as is practicable, or at such other time thereafter as our counsel, Troutman Pepper Locke LLP, may request
by telephone. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Troutman
Pepper Locke LLP, by calling Eric D. Kline at (412) 454-5046 or Gregory Rubis at (609) 951-4105.
Please
direct any questions or comments concerning this request to Eric Kline or Gregory Rubis.
ENSYSCE
BIOSCIENCES, Inc.
By:
/s/
Lynn Kirkpatrick
Name:
Dr.
Lynn Kirkpatrick
Title:
President
and Chief Executive Officer
cc:
Eric
D. Kline, Troutman Pepper Locke LLP
Gregory
Rubis, Troutman Pepper Locke LLP