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CORRESP Filing

Ensysce Biosciences, Inc.
Date: Dec. 9, 2025 · CIK: 0001716947 · Accession: 0001493152-25-026751

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File numbers found in text: 333-291892

Date
Dec. 9, 2025
Author
President
Form
CORRESP
Company
Ensysce Biosciences, Inc.

Letter

Ensysce Biosciences, Inc.

Ivanhoe Avenue, Suite 201

La Jolla, California 92037

December 9, 2025

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

F Street, NE

Washington, D.C. 20549

Attention: Timothy L. Buchmiller, Esq.

Re: Ensysce Biosciences, Inc.

Registration Statement on Form S-3

SEC File No. 333-291892

Filed December 2, 2025

Ladies and Gentlemen:

Pursuant to Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, Ensysce Biosciences, Inc. hereby requests that the effective date of the above-referenced Registration Statement be accelerated to 4:00 PM, Eastern Time, on December 11, 2025, or as soon thereafter as is practicable, or at such other time thereafter as our counsel, Troutman Pepper Locke LLP, may request by telephone. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Troutman Pepper Locke LLP, by calling Eric D. Kline at (412) 454-5046 or Gregory Rubis at (609) 951-4105.

Please direct any questions or comments concerning this request to Eric Kline or Gregory Rubis.

ENSYSCE BIOSCIENCES, Inc.

By:

/s/ Lynn Kirkpatrick

Name: Dr. Lynn Kirkpatrick

Title: President and Chief Executive Officer

cc:

Eric D. Kline, Troutman Pepper Locke LLP

Gregory Rubis, Troutman Pepper Locke LLP

Show Raw Text
CORRESP
1
filename1.htm

Ensysce
Biosciences, Inc.

7946
Ivanhoe Avenue, Suite 201

La
Jolla, California 92037

December
9, 2025

VIA
EDGAR

U.S.
Securities and Exchange Commission

Division
of Corporation Finance

Office
of Life Sciences

100
F Street, NE

Washington,
D.C. 20549

Attention:
Timothy L. Buchmiller, Esq.

    Re:
    Ensysce
    Biosciences, Inc.

    Registration
    Statement on Form S-3

    SEC
    File No. 333-291892

    Filed
    December 2, 2025

Ladies
and Gentlemen:

Pursuant
to Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, Ensysce Biosciences, Inc.
hereby requests that the effective date of the above-referenced Registration Statement be accelerated to 4:00 PM, Eastern Time, on December
11, 2025, or as soon thereafter as is practicable, or at such other time thereafter as our counsel, Troutman Pepper Locke LLP, may request
by telephone. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Troutman
Pepper Locke LLP, by calling Eric D. Kline at (412) 454-5046 or Gregory Rubis at (609) 951-4105.

Please
direct any questions or comments concerning this request to Eric Kline or Gregory Rubis.

    ENSYSCE
    BIOSCIENCES, Inc.

    By:

    /s/
    Lynn Kirkpatrick

    Name:
    Dr.
    Lynn Kirkpatrick

    Title:
    President
    and Chief Executive Officer

    cc:

    Eric
    D. Kline, Troutman Pepper Locke LLP

    Gregory
    Rubis, Troutman Pepper Locke LLP