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UPLOAD Filing

Jade Biosciences, Inc.
Date: Dec. 23, 2025 · CIK: 0001798749 · Accession: 0000000000-25-011803

Regulatory Compliance Offering / Registration Process Financial Reporting

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File numbers found in text: 333-292369

Date
December 23, 2025
Author
Tom Frohlich
Form
UPLOAD
Company
Jade Biosciences, Inc.

Letter

December 23, 2025 Tom Frohlich Chief Executive Officer Jade Biosciences, Inc. 221 Crescent St., Building 23 Suite 105 Waltham, MA 02453 Re:Jade Biosciences, Inc. Registration Statement on Form S-1 Filed December 22, 2025 File No. 333-292369 Dear Tom Frohlich: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tim Buchmiller at 202-551-3635 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc:Anthony Gostanian, Esq.

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December 23, 2025
Tom Frohlich
Chief Executive Officer
Jade Biosciences, Inc.
221 Crescent St., Building 23
Suite 105
Waltham, MA 02453
Re:Jade Biosciences, Inc.
Registration Statement on Form S-1
Filed December 22, 2025
File No. 333-292369
Dear Tom Frohlich:
            This is to advise you that we have not reviewed and will not review your registration
statement.
            Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you
that the company and its management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action by the staff.
            Please contact Tim Buchmiller at 202-551-3635 with any questions.
Sincerely,
Division of Corporation Finance
Office of Life Sciences
cc:Anthony Gostanian, Esq.