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CORRESP Filing

Jade Biosciences, Inc.
Date: Dec. 23, 2025 · CIK: 0001798749 · Accession: 0001193125-25-330829

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File numbers found in text: 333-292369

Date
December 23, 2025
Author
Bradford Dahms
Form
CORRESP
Company
Jade Biosciences, Inc.

Letter

Re: Jade Biosciences, Inc. Registration Statement on Form S-1 File No. 333-292369 Ladies and Gentlemen: In accordance with Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the above-referenced Registration Statement on Form S-1 (the “Registration Statement”) of Jade Biosciences, Inc. (the “Company”). We respectfully request that the Registration Statement become effective as of 4:00 p.m. Eastern Time on December 30, 2025, or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Latham & Watkins LLP, by calling Matt Bush at (858) 523-3962. Thank you for your assistance in this matter.

Jade Biosciences, Inc. 221 Crescent Street, Building 23, Suite 105 Waltham, Massachusetts 02453 December 23, 2025 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549-6010 Attn: Mr. Jimmy McNamara

Very truly yours,
JADE BIOSCIENCES, INC.

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CORRESP
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 CORRESP

 Jade Biosciences, Inc.
 221 Crescent Street, Building 23, Suite 105
 Waltham, Massachusetts 02453
 December 23, 2025 VIA EDGAR
 United States Securities and Exchange Commission
 Division of Corporation Finance Office of Life Sciences
 100 F Street, N.E. Washington, D.C. 20549-6010
 Attn: Mr. Jimmy McNamara

 Re:
 Jade Biosciences, Inc.
 Registration Statement on Form S-1
 File No. 333-292369
 Ladies and Gentlemen: In accordance with Rule
461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the above-referenced Registration Statement on
Form S-1 (the “Registration Statement”) of Jade Biosciences, Inc. (the “Company”). We respectfully request that the Registration Statement become effective as of 4:00 p.m. Eastern Time
on December 30, 2025, or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Latham & Watkins LLP, by calling Matt Bush at (858) 523-3962. Thank you for your assistance in this matter.

 Very truly yours,

 JADE BIOSCIENCES, INC.

 By:

 /s/ Bradford Dahms

 Bradford Dahms

 Chief Financial Officer

 cc:
 Tom Frohlich, Jade Biosciences, Inc.
 Elizabeth Balta, Jade Biosciences, Inc.
 Cheston Larson, Latham & Watkins LLP
 Matthew T. Bush, Latham & Watkins LLP
 Anthony Gostanian, Latham & Watkins LLP