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UPLOAD Filing

ASSEMBLY BIOSCIENCES, INC.
Date: March 24, 2026 · CIK: 0001426800 · Accession: 0000000000-26-002988

Offering / Registration Process Regulatory Compliance Financial Reporting

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File numbers found in text: 333-294459

Date
March 24, 2026
Author
Jason A. Okazaki
Form
UPLOAD
Company
ASSEMBLY BIOSCIENCES, INC.

Letter

March 24, 2026 Jason A. Okazaki Chief Executive Officer and President Assembly Biosciences, Inc. Two Tower Place, 7th Floor South San Francisco, California 94080 Re:Assembly Biosciences, Inc. Registration Statement on Form S-3 Filed March 19, 2026 File No. 333-294459 Dear Jason A. Okazaki: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Chris Edwards at 202-551-6761 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc:P. Michelle Gasaway, Esq.

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March 24, 2026
Jason A. Okazaki
Chief Executive Officer and President
Assembly Biosciences, Inc.
Two Tower Place, 7th Floor
South San Francisco, California 94080
Re:Assembly Biosciences, Inc.
Registration Statement on Form S-3
Filed March 19, 2026
File No. 333-294459
Dear Jason A. Okazaki:
            This is to advise you that we have not reviewed and will not review your registration
statement.
            Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you
that the company and its management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action by the staff.
            Please contact Chris Edwards at 202-551-6761 with any questions.
Sincerely,
Division of Corporation Finance
Office of Life Sciences
cc:P. Michelle Gasaway, Esq.