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CORRESP Filing

ASSEMBLY BIOSCIENCES, INC.
Date: March 25, 2026 · CIK: 0001426800 · Accession: 0001193125-26-124050

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File numbers found in text: 333-294459

Date
March 19, 2026
Author
John O. Gunderson
Form
CORRESP
Company
ASSEMBLY BIOSCIENCES, INC.

Letter

March 25, 20236 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Assembly Biosciences, Inc. Registration Statement on Form S-3 Filed March 19, 2026 File No. 333-294459 Request for Acceleration of Effective Date Ladies and Gentlemen: Pursuant to Rule 461 of the Securities Act of 1933, as amended, Assembly Biosciences, Inc. (the “Company”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-294459) (the “Registration Statement”) to 4:30 p.m. Eastern Time on Friday, March 27, 2026 or as soon thereafter as practicable. The Company acknowledges that both the Company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff of the U.S. Securities and Exchange Commission. Please contact P. Michelle Gasaway of Skadden, Arps, Slate, Meagher & Flom LLP, special counsel to the Company, at +1.213.687.5122 as soon as the Registration Statement has been declared effective or if you have any other questions or concerns regarding this matter. Regards, By: /s/ John O. Gunderson Name: John O. Gunderson Title: VP, General Counsel and Corporate Secretary cc: P. Michelle Gasaway Skadden, Arps, Slate, Meagher & Flom LLP Jason A. Okazaki Assembly Biosciences, Inc. Two Tower Place, 7th Floor, South San Francisco, CA 94080

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CORRESP
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 filename1.htm

 CORRESP

 March 25, 20236   Via EDGAR   Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549   Re: Assembly Biosciences, Inc. Registration Statement on Form S-3 Filed March 19, 2026 File No. 333-294459 Request for Acceleration of Effective Date   Ladies and Gentlemen:   Pursuant to Rule 461 of the Securities Act of 1933, as amended, Assembly Biosciences, Inc. (the “Company”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-294459) (the “Registration Statement”) to 4:30 p.m. Eastern Time on Friday, March 27, 2026 or as soon thereafter as practicable.   The Company acknowledges that both the Company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff of the U.S. Securities and Exchange Commission.   Please contact P. Michelle Gasaway of Skadden, Arps, Slate, Meagher & Flom LLP, special counsel to the Company, at +1.213.687.5122 as soon as the Registration Statement has been declared effective or if you have any other questions or concerns regarding this matter.   Regards,   By: /s/ John O. Gunderson Name: John O. Gunderson Title: VP, General Counsel and Corporate Secretary     cc: P. Michelle Gasaway Skadden, Arps, Slate, Meagher & Flom LLP Jason A. Okazaki Assembly Biosciences, Inc.
 Two Tower Place, 7th Floor, South San Francisco, CA 94080