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SEC Comment Letter for Silence Therapeutics (SLN) — May 22, 2026

Silence Therapeutics plc
Date: May 22, 2026 · CIK: 0001479615 · Accession: 0000000000-26-005242

Offering / Registration Process

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File numbers found in text: 333-295992

Date
May 22, 2026
Author
Division of
Form
UPLOAD
Company
Silence Therapeutics plc

Letter

Re: Silence Therapeutics plc Registration Statement on Form S-3 Filed May 18, 2026 File No. 333-295992 Dear Rhonda Hellums: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Doris Stacey Gama at 202-551-3188 with any questions.

May 22, 2026

Rhonda Hellums Chief Financial Officer Silence Therapeutics plc 221 River Street, 9th Floor Hoboken, NJ 07030

Sincerely,
Division of
Corporation Finance
Office of Life
Sciences
cc: Denny Xu, Esq.

Show Raw Text
<DOCUMENT>
<TYPE>TEXT-EXTRACT
<SEQUENCE>2
<FILENAME>filename2.txt
<TEXT>
 May 22, 2026

Rhonda Hellums
Chief Financial Officer
Silence Therapeutics plc
221 River Street, 9th Floor
Hoboken, NJ 07030

 Re: Silence Therapeutics plc
 Registration Statement on Form S-3
 Filed May 18, 2026
 File No. 333-295992
Dear Rhonda Hellums:
 This is to advise you that we have not reviewed and will not review your
registration
statement.
 Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you that
the company and its management are responsible for the accuracy and adequacy of
their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.
 Please contact Doris Stacey Gama at 202-551-3188 with any questions.

 Sincerely,

 Division of
Corporation Finance
 Office of Life
Sciences
cc: Denny Xu, Esq.
</TEXT>
</DOCUMENT>