SEC Company Response from Silence Therapeutics (SLN) — May 22, 2026
Silence Therapeutics plc
Date: May 22, 2026 · CIK: 0001479615 · Accession: 0001193125-26-236865
AI Filing Summary & Sentiment
Reasoning
File numbers found in text: 333-295992
Letter
Re: Silence Therapeutics plc Registration Statement on Form S-3 File No. 333-295992 Acceleration Request Requested Date: May 27, 2026 Requested Time: 4:00 PM Eastern Time Ladies and Gentlemen: In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant (the “ Registrant ”) hereby requests that the Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the Registration Statement on Form S-3 (File No.: 333-295992) (the “ Registration Statement ”) to become effective on Wednesday, May 27, 2026 at 4:00 p.m. Eastern Time, or as soon as practicable thereafter, or at such later time as the Registrant may orally request via telephone call to the staff of the Commission. The Registrant hereby authorizes Eric Blanchard of Cooley LLP, counsel to the Registrant, to make such request on its behalf. Once the Registration Statement has been declared effective, please orally confirm that event with Eric Blanchard of Cooley LLP, counsel to the Registrant, at (617) 937-2445.
SILENCE THERAPEUTICS PLC 12 Hammersmith Grove London W6 7AP, United Kingdom +44 20 3457 6900 May 22, 2026 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Doris Stacey Gama
Very truly yours,
Silence Therapeutics plc
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CORRESP 1 filename1.htm CORRESP SILENCE THERAPEUTICS PLC 12 Hammersmith Grove London W6 7AP, United Kingdom +44 20 3457 6900 May 22, 2026 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Doris Stacey Gama Re: Silence Therapeutics plc Registration Statement on Form S-3 File No. 333-295992 Acceleration Request Requested Date: May 27, 2026 Requested Time: 4:00 PM Eastern Time Ladies and Gentlemen: In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant (the “ Registrant ”) hereby requests that the Securities and Exchange Commission (the “ Commission ”) take appropriate action to cause the Registration Statement on Form S-3 (File No.: 333-295992) (the “ Registration Statement ”) to become effective on Wednesday, May 27, 2026 at 4:00 p.m. Eastern Time, or as soon as practicable thereafter, or at such later time as the Registrant may orally request via telephone call to the staff of the Commission. The Registrant hereby authorizes Eric Blanchard of Cooley LLP, counsel to the Registrant, to make such request on its behalf. Once the Registration Statement has been declared effective, please orally confirm that event with Eric Blanchard of Cooley LLP, counsel to the Registrant, at (617) 937-2445. Very truly yours, Silence Therapeutics plc By: /s/ Iain Ross Iain Ross Interim Principal Executive Officer cc: Rhonda Hellums, Silence Therapeutics plc Eric Blanchard, Cooley LLP Courtney T. Thorne, Cooley LLP Denny Xu, Cooley LLP