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CORRESP Filing

Jaguar Health, Inc.
Date: June 25, 2025 · CIK: 0001585608 · Accession: 0001193125-25-146825

Offering / Registration Process

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File numbers found in text: 333-288202

Date
June 25, 2025
Author
Lisa A. Conte
Form
CORRESP
Company
Jaguar Health, Inc.

Letter

Re: Jaguar Health, Inc. Registration Statement on Form S-3 File No. 333-288202 Ladies and Gentlemen: Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Jaguar Health, Inc., a Delaware corporation (the “ Registrant ”), hereby requests the above-referenced Registration Statement on Form S-3 (the “ Registration Statement ”) be declared effective by the Securities and Exchange Commission on Friday, June 27, 2025, at 4:00 p.m., Eastern Time, or as soon thereafter as is practicable. The Registrant hereby authorizes each of Donald C. Reinke, Esq. and Michael S. Lee, Esq. of Reed Smith LLP, attorneys for the Registrant, to orally modify or withdraw this request for acceleration. Please confirm effectiveness by advising our counsel, Michael S. Lee of Reed Smith LLP, at (212) 549-0358. Very truly yours,

CORRESP - SEC Acceleration Request

June 25, 2025 Via EDGAR U.S. Securities and Exchange Commission 100 F Street, N.E. Washington, D.C. 20549

Jaguar Health, Inc.

/s/ Lisa A. Conte

Lisa A. Conte

Chief Executive Officer and President Jaguar Health, Inc. • 200 Pine Street, Suite 400 • San Francisco, CA 94104 Tel : +1 (415) 371-8300 • Fax: +1 (415) 371-8311 • https://jaguar.health

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CORRESP
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 CORRESP - SEC Acceleration Request

 June 25, 2025
 Via EDGAR U.S. Securities and Exchange Commission
 100 F Street, N.E. Washington, D.C. 20549

 Re:
 Jaguar Health, Inc.
 Registration Statement on Form S-3
 File No. 333-288202
 Ladies and Gentlemen: Pursuant to Rule 461
promulgated under the Securities Act of 1933, as amended, Jaguar Health, Inc., a Delaware corporation (the “ Registrant ”), hereby requests the above-referenced Registration Statement on Form
 S-3 (the “ Registration Statement ”) be declared effective by the Securities and Exchange Commission on Friday, June 27, 2025, at 4:00 p.m., Eastern Time, or as soon thereafter as is
practicable. The Registrant hereby authorizes each of Donald C. Reinke, Esq. and Michael S. Lee, Esq. of Reed Smith LLP, attorneys for
the Registrant, to orally modify or withdraw this request for acceleration. Please confirm effectiveness by advising our counsel, Michael
S. Lee of Reed Smith LLP, at (212) 549-0358. Very truly yours,

 Jaguar Health, Inc.

 /s/ Lisa A. Conte

 Lisa A. Conte

 Chief Executive Officer and President
 Jaguar Health, Inc. • 200 Pine Street, Suite 400 • San Francisco, CA 94104
 Tel : +1 (415) 371-8300 • Fax: +1 (415)
 371-8311 • https://jaguar.health