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CORRESP Filing

SOPHiA GENETICS SA (SOPH) (CIK 0001840706)
Date: Aug. 13, 2025 · CIK: 0001840706 · Accession: 0000950103-25-010240

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File numbers found in text: 333-289266

Date
August 13, 2025
Author
SOPHiA GENETICS SA
Form
CORRESP
Company
SOPHiA GENETICS SA (SOPH) (CIK 0001840706)

Letter

Re: SOPHiA GENETICS SA Registration Statement on Form F-3 Registration No. 333-289266

August 13, 2025

VIA EDGAR

Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form F-3 (File No. 333-289266) (as amended, the "Registration Statement") of SOPHiA GENETICS SA. We respectfully request that the Registration Statement be declared effective as of 4:00 p.m., Eastern time, on August 15, 2025 or as soon as practicable thereafter.

Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Davis Polk & Wardwell LLP, by calling Sierra Acosta at (212) 450-3504.

Thank you for your assistance in this matter.

Sincerely,
SOPHiA GENETICS SA

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CORRESP
 1
 filename1.htm

 August 13, 2025

 VIA EDGAR

 Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549

 Re:
 SOPHiA GENETICS SA
Registration Statement on Form F-3
Registration No. 333-289266

 Ladies and Gentlemen:

 In accordance with Rule 461 under the Securities Act of 1933, as amended,
we hereby request acceleration of the effective date of the Registration Statement on Form F-3 (File No. 333-289266) (as amended, the
"Registration Statement") of SOPHiA GENETICS SA. We respectfully request that the Registration Statement be declared effective
as of 4:00 p.m., Eastern time, on August 15, 2025 or as soon as practicable thereafter.

 Once the Registration Statement has been declared effective, please
orally confirm that event with our counsel, Davis Polk & Wardwell LLP, by calling Sierra Acosta at (212) 450-3504.

 Thank you for your assistance in this matter.

 Sincerely,

 SOPHiA GENETICS SA

 By:
 /s/ Daan van Well

 Name:	Daan van Well

 Title:	Chief Legal & Regulatory Officer