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Correspondence 0001104659-26-028073 from Aprea Therapeutics, Inc. (APRE)

Aprea Therapeutics, Inc.
Date: March 16, 2026 · CIK: 0001781983 · Accession: 0001104659-26-028073

Financial Reporting Regulatory Compliance Offering / Registration Process

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File numbers found in text: 333-293609

Referenced dates: February 24, 2026

Date
February 20, 2026
Author
Partner
Form
CORRESP
Company
Aprea Therapeutics, Inc.

Letter

VIA EDGAR Division of Corporation Finance U.S. Securities and Exchange Commission 100 F Street, N.E. Washington, D.C. 20549 Attention: Alan Campbell File No. 333-293609

Re: Aprea Therapeutics, Inc. (the "Company") Registration Statement on Form S-3 Filed February 20, 2026

Dear Mr. Campbell:

This letter is submitted on behalf of the Company in response to the Staff's comment letter dated February 24, 2026 (the "Comment Letter") relating to the above-referenced Registration Statement on Form S-3 (the "Registration Statement").

Staff Comment 1. We note that you filed this registration statement more than 45 days after the end of your fiscal year. As such, you do not appear to meet the age of financial statement requirements of Rule 8-08(b) of Regulation S-X. Please revise to include audited financial statements for the fiscal year ended December 31, 2025.

Company Response. The Company respectfully advises the Staff that the Company has filed its Annual Report on Form 10-K for the fiscal year ended December 31, 2025, on March 16, 2026. As a result, the audited financial statements for the fiscal year ended December 31, 2025, are now on file with the Commission and incorporated by reference into the Registration Statement in accordance with the incorporation by reference provisions of the Registration Statement.

The Company respectfully believes that the filing of the Form 10-K addresses the Staff's comment. The Company acknowledges the Staff may have further questions and will respond promptly to any additional comments.

Please do not hesitate to contact the undersigned at 206-839-4831with any questions.

Sincerely,
Patrick O'Malley, Esq.
Partner
DLA Piper LLP US

Show Raw Text
CORRESP
 1
 filename1.htm

 VIA EDGAR
Division of Corporation Finance
U.S. Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C. 20549

 Attention: Alan Campbell

 Re: Aprea Therapeutics, Inc. (the "Company")
Registration Statement on Form S-3
Filed February 20, 2026

 File No. 333-293609

 Dear Mr. Campbell:

 This letter is submitted on behalf of the Company
in response to the Staff's comment letter dated February 24, 2026 (the "Comment Letter") relating to the above-referenced
Registration Statement on Form S-3 (the "Registration Statement").

 Staff Comment 1. We note that you filed
this registration statement more than 45 days after the end of your fiscal year. As such, you do not appear to meet the age of financial
statement requirements of Rule 8-08(b) of Regulation S-X. Please revise to include audited financial statements for the fiscal year ended
December 31, 2025.

 Company Response. The Company respectfully
advises the Staff that the Company has filed its Annual Report on Form 10-K for the fiscal year ended December 31, 2025, on March 16,
2026. As a result, the audited financial statements for the fiscal year ended December 31, 2025, are now on file with the Commission and
incorporated by reference into the Registration Statement in accordance with the incorporation by reference provisions of the Registration
Statement.

 The Company respectfully believes that the filing
of the Form 10-K addresses the Staff's comment. The Company acknowledges the Staff may have further questions and will respond promptly
to any additional comments.

 Please do not hesitate to contact the undersigned
at 206-839-4831with any questions.

 Sincerely,

 Patrick O'Malley, Esq.
Partner
DLA Piper LLP US

 cc: Oren Gilad
cc: John Hamill